Institute of Biology - Bucharest







Research projects








Plant and Animal Cytobiology Department

Head of the Department: Dr. Manole Anca, Senior Researcher III, Head of the Department

Research directions:

A. Plant Cytobiology

- cellular and biochemical characterization of developmental processes in In vitro systems on threatened plant species from Romania’s Flora for ex situ conservation and biotechnological applications.


1. Higher plants


- Species having a short and medium term conservation protocol:


Artemisia tschernieviana Besser (Asteraceae)

Astragalus pseudopurpureus Gusul. (Fabaceae)

Cerastium transsilvanicum Schur. (Caryophyllaceae)

Doronicum carpaticum (Griseb. et Schenk) Nyman (Asteraceae)

Hieracium pojoritense Wol. (Asteraceae)

Campanula carpatica Jacq. (Campanulaceae)

Alyssum borzaeanum Nyar. (Brassicaceae)

- Species in in vitro culture maintaining for short and medium term:


Dianthus callizonus Schott et Kotschy (Caryophyllaceae)

Dianthus glacialis Haencke subsp. gelidus (Schott, Nyman et Kotschy) Tutin (Caryophyllaceae)

Dianthus spiculifolius Schur. (Caryophyllaceae)

Dianthus tenuifolius Schur. (Caryophyllaceae)

Gypsophyla petraea (Baumg.) Reichenb. (Caryophyllaceae)

Veronica multifida L. ssp. capsellicarpa Jelen (Scrophulariaceae)

Erigeron nanus Schur (Asteraceae)

Gentiana lutea L. (Gentianaceae)

Primula halleri J.F. Gmelin (Primulaceae)

Armeria maritima (Mill.) Willd. ssp. alpina Willd. (Plumbaginaceae)

Ecballium elaterium L. (Cucurbitaceae)

Ruscus aculeatus L. (Liliaceae)

Marsilea quadrifolia L. (Marsileaceae)

Crocus flavus Weston (Iridaceae)


2. Bryophytes

Plagiothecium undulatum (Hedwig) Schimp. (Plagiotheciaceae)

Bucegia romanica Radian (Marchantiaceae)

Preissia quadrata (Scop.) Nees (Marchantiaceae)

Calliergonella cuspidata (Hedw.) Loeske (Amblystegiaceae)

Marchantia polymorpha L. (Marchantiaceae)

Conocephalum conicum (L.) Underw. (Conocephalaceae)

Brachyotecium ssp. Schimp. (Brachytheciaceae)

Philonotis fontana (Hedw.) Brid. (Bartramiaceae)

Mnium hornum Hedw. (Mniaceae)

Plagiomnium rostratum (Schrad.) T.J. Kop. (Mniaceae)

Atrichum undulatum (Hedw.) P. Beauv. (Polytrichaceae)

Athalamia hyalina (Sommerf.) S. Hatt. (Cleveaceae)

Leiocolea bantriensis (Hook.) Steph. (Lophoziaceae)

Aulacomnium androgynum (Hedw.) Schwaegr. (Aulocomniaceae)


3. Lichens

Cetraria islandica (L.) Ach. (Parmeliaceae )

Xanthoria parietina (L.) Th. Fr. (Teloschistaceae)

Usnea barbata (L.) Mott. (Usneaceae )

- Organization of an active gene bank of plant tissue cultures in order to preserve endangered wild species from autochthon flora.

- Use the in vitro cell and tissue cultures system for identifying and characterizing of secondary metabolites of biotechnological interest.

B. Animal Cytobiology

-  Cell and molecular interactions at the tumor-peritumoral stroma interface;

- The role of activated stroma during carcinogenesis and tumor angiogenesis;

- Study of the modulator effects of the peritumoral stroma during invasivity and reversion of the malignant phenotype.

Research team:

Dr. Manole Anca, Senior Researcher III, Head of the Department

Dr. Mirancea Nicolae, Senior Researcher I

Dr. Cogalniceanu Gina-Carmen, Senior Researcher II

Dr. Holobiuc Mihaela Irina, Senior Researcher III

Dr. Mitoi Elena Monica, Senior Researcher III

Dr. Maximilian Rodica Carmen, Senior Researcher III

Dr. Banciu Cristian, Senior Researcher III

Dr. Catană Rodica, Senior Researcher III

Dr. Helepciuc Florenta-Elena, Researcher

Dr. Moroşanu Ana Maria, Researcher

Dr. Voicu Diana Marcela Florentina, Researcher

Dr. Aldea Florentina, Junior Researcher

Maria Gabriel Mihai, Junior Researcher, PhD Student

Vladimirescu Mihnea, Junior Researcher, PhD Student



Dr. Brezeanu Aurelia, Senior Researcher I



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Last modified: 02/28/21